MRI brain volume analysis using NeuroQuant^® software

NeuroQuant^® is an exciting development for uncovering evidence of brain injury in our patients with mild to moderate traumatic brain injury. Most patients with mild to moderate traumatic brain injury (TBI) have normal CT scans and MRI scans. For years, advances in structural brain imaging have promised to remedy this situation. Finally, the promises of the research laboratory are readily available for everyday patients in the clinic.

NeuroQuant^® is a software program cleared by the FDA for measuring brain MRI volume. NeuroQuant^® automatically identifies several MRI brain regions and measures the volume of each. These data are then compared to MRI data from normal control subjects. In addition to the NeuroQuant^® standard report (which measures 11 brain regions but compares only 3 regions to normal controls) we have extended the utility of the test by comparing all 11 regions to normal controls, and by examining longitudinal change (obtaining 2 MRIs in the same patient, several months apart, and looking for progressive atrophy).